Won a Daytime Emmy Award for Outstanding Ingenue in a Drama Series in 1988 for her career-launching role on the CBS soap opera As the World Turns
Made her big-screen debut in Tales From the Darkside: The Movie (1990)
Met her third husband, director Bart Freundlich, while acting in his 1996 film Myth of Fingerprints
Donated a suit from the 1999 drama The End of the Affair to an auction benefiting Planned Parenthood
Bought the movie rights to the book Raveling, which was written by her brother, Peter Moore Smith, in 2001
Starting with Freckleface Strawberry in 2007, has authored a series of children's books about her experiences growing up; an off-Broadway musical inspired by the books debuted in 2010
Has been a spokesmodel for Bulgari, Revlon and Talbots
Is a longtime supporter of the Tuberous Sclerosis Alliance, a nonprofit dedicated to finding a cure for the genetic disorder